发明名称 HIGH MOLECULAR WEIGHT MENINGOCOCCAL GROUP C VACCINE AND METHOD FOR PREPARATION THEREOF
摘要 A vaccine against Group C meningococcal meningitis consisting of a polysaccharide of which at least 80% by weight has a molecular weight in excess of 1,000,000 daltons is prepared. The polysaccharide was isolated from Group C hexadecyl trimethylammonium bromide cell paste with 1.0M CaCl2 extraction and purified by phenol extraction, ultracentrifugation at 100,000 g. and ethanol fractionation (30%-45% v/v in ethanol).
申请公布号 ZA7804324(B) 申请公布日期 1980.03.26
申请号 ZA19780004324 申请日期 1978.07.31
申请人 MERCK & CO INC 发明人 CARLO D;HAGOPIAN A;STOUDT T
分类号 C12P19/04;A61K39/095 主分类号 C12P19/04
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