发明名称 Process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid and of the addition salts of this acid
摘要 Substituted phenyl N-(2,6-dichlorophenyl)benzymidate, obtained by condensation of a salt of 2,6-dichlorophenol with the imidoyl chloride, is converted by the Chapman rearrangement to the compound of formula <IMAGE> in which Q is a radical chosen from the cyano and alkoxycarbonyl groups and Z is a substituted or unsubstituted phenyl group. By hydrolysis of the compound (III), o-(2,6-dichloroanilino)phenylacetic acid is obtained. This compound is useful as an analgesic and non-steroidal anti-inflammatory agent.
申请公布号 CH610877(A5) 申请公布日期 1979.05.15
申请号 CH19760003790 申请日期 1976.03.26
申请人 IKEDA MOHANDO CO. LTD. 发明人 FUJIO NOHARA
分类号 A61K31/19;A61K31/195;A61K31/196;C07C;C07C67/00;C07C227/00;C07C227/18;C07C227/20;C07C229/42;C07C241/00;C07C257/08;(IPC1-7):C07C101/44 主分类号 A61K31/19
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