发明名称 N-Carbobenzoxy-N{40 -(2-nitrophenyl)-2-piperazine carboxylic acid
摘要 Compounds of the formula <IMAGE> <IMAGE> wherein R is hydrogen (lower)alkyl, phen(lower)alkyl, benzoyl(lower)alkyl, or p-halobenzoyl(lower)alkyl; R1 is hydrogen or (lower)alkyl; R2 is hydrogen, (lower)alkyl, (lower)alkoxy, chlorine, fluorine, trifluoromethyl, or amino in the 7-, 8-, or 9-position; R3 is hydrogen, or (lower)alkyl; and R4 is hydrogen, (lower)alkyl, (lower)alkoxy, chlorine, fluorine, or trifluoromethyl in the 7-, 8-, or 9-position; or the non-toxic acid addition salts thereof; exert a hypotensive effect in hypertensive animals.
申请公布号 US4138567(A) 申请公布日期 1979.02.06
申请号 US19770835560 申请日期 1977.09.22
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 FREED, MEIER E.;POTOSKI, JOHN R.
分类号 C07C205/12;C07D239/42;C07D241/04;C07D487/04;C07F1/00;C07F1/08;(IPC1-7):C07D241/18;C07D241/06 主分类号 C07C205/12
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