发明名称 |
Cis-4,5-didehydro-13,14-didehydro-11-deoxy-17-phenyl-18,19,20-trinon-PGE, compounds |
摘要 |
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
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申请公布号 |
US4130718(A) |
申请公布日期 |
1978.12.19 |
申请号 |
US19770820980 |
申请日期 |
1977.08.01 |
申请人 |
THE UPJOHN COMPANY |
发明人 |
SMITH, HERMAN W. |
分类号 |
A61K31/23;A61P43/00;C07C35/27;C07C51/347;C07C51/60;C07C53/21;C07C57/30;C07C57/72;C07C67/00;C07C401/00;C07C405/00;C07D307/935;C07D317/14;C07F9/38;C07F9/40;C07F9/54;(IPC1-7):C07C177/00 |
主分类号 |
A61K31/23 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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