Acaricidal N-substd. phenyl formamide oxime derivs. - partic. active against ticks of ixodidae and sarcosporidae families

摘要

N-phenyl-formamide oximes of formula (I) and their acid addition salts are new: (where n=1-3 and each R independenyl=halo, alkyl, alkoxy, alkythio, acyl, alkylamino, dialkylamino, hydroxy, CF3, phenoxy, halo-phenoxy, phenylthio, benzoyl, amino or nitro. the alkyl and acyl groups are 'lower'). (I) have low toxicity to warm blodded animals. (I) are active against ectoparasites of ixodidae (hard ticks) and sarcosporidia e.g. Boophilus microplus, Boophilus decoloratus, single-host blue ticks and ticks of species Hyalomma, Rhipicephalus, Amblyomma, Haemophysalis, Dermacentor and Ixodes. The cpds. are active against all stage of development of the ticks and cause abandonment of the host. (I) are generally applied as aq. sprays or drenchs contg. 0.01-5% of active cpd. Cpds (I) where (Rn)=2, 4-dimethyl; 2-methyl-4-chloro and 4-phenoxy are specifically claimed.