Pyrimidinyl phosphate or phosphonate ester and amide derivs. - and sulphur analogues useful as insecticides, acaricides and nematocides

摘要

Phosphorus esters of formula (I) are new: (where R is alkyl; R1 is alkyl, alkoxy, alkylthio, monoalkylamino or phenyl; R2 is H, alkyl or phenyl; R3 is H or alkyl and X is O or S). They are prepd. e.g. by reacting a 5-hydroxypyrimidine with X = P(OR)(R1)Hal. (I) have insecticidal, acaricidal and nematocidal effects. They are more active than known cpds., of similar structure and are useful in plant protection, for hygienic applications, for protection of stored goods and in veterinary medicine. In an example, 0,0-diethyl, 0- 2-isopropylpyrimidin-5-yl -thionophosphate was prepd. from 2-isopropyl-5-hydroxypyrimidine and 0,0-diethyl-thionophosphonyl chloride.