| 摘要 |
<p>Prepn. of benzhydrol cpds. (I): (in which one or both rings are substd.; X1 and X2 are H, lower alkyl, lower alkoxy or lower alkylthio; A is F, lower alkyl, lower alkoxy, CF3 or OCF3 and n = 0-3), comprises (a) reacting a halobenzene cpd. (II) (in which Hal = Cl, Br or I), with magnesium to form (III): and (b) condensing (III) with a lower alkyl formate HCOOR, (in which R is opt. branched 1-6C alkyl). Process is relatively simple and gives high yields of (I), which are useful intermediates in the prepn. of diarylacetonitriles, diarylhalomethanes and diarylacetic acids.</p> |
