发明名称 Analgetic composition
摘要 An alalgetic composition which comprises, as an active ingredient, a therapeutically effective amount of a synergistic mixture of an indole-3-acetic acid derivative of the formula, <IMAGE> wherein R is a halobenzoyl, piperonyloyl or cinnamoyl group and R1 is a 5-methoxy or 5,6-methylenedioxy group; and a narcotic or anti-narcotic analgesic selected from the group consisting of a compound of the formula, <IMAGE> wherein R2 and R3 are each a C1 - C3 alkyl group and R4 is a 4-(4-fluorophenyl)-4-oxobutyl, cyclopropylmethyl or 3-methyl-2-butenyl group; a compound of the formula, <IMAGE> wherein R5 is a hydrogen atom or a C1 - C3 alkyl group; a compound of the formula, <IMAGE> and a compound of the formula, <IMAGE> wherein R6 is a C1 - C3 alkyl group; and a pharmaceutically acceptable carrier or diluent and its preparation and a method of obtaining analgesia which comprises administering the same to a patient.
申请公布号 US4029798(A) 申请公布日期 1977.06.14
申请号 US19750582757 申请日期 1975.06.02
申请人 SUMITOMO CHEMICAL COMPANY, LIMITED 发明人 YAMAMOTO, HISAO;INUKAI, TOSHIYA;KOGA, YOSHIHIKO
分类号 C07D209/28;A61K31/40;A61K31/403;A61K31/404;A61K31/405;A61K31/435;A61K31/445;A61K31/485;A61P25/04;C07D211/64;C07D221/28;(IPC1-7):A61K31/48 主分类号 C07D209/28
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