发明名称 BASE FOR OPHTHALMOLOGICAL MEDICINAL PREPARATIONS AND AN OPHTHALMOLOGICAL MEDICINAL FILM
摘要 <p>A base for ophthalmological medicinal preparations consists of at least one polymer selected from a homopolymer of an amide of acrylic acid having a molecular weight from 30,000 to 1,000,000, and a copolymer of an amide of acrylic acid with unsaturated compounds from the group consisting of N-vinylpyrrol-idone, ethyl acrylate, butyl acrylate, N-vinylcaprolactam, vinyl acetate, the molecular weight of the copolymer being from 20,000 to 500,000, and containing from 10 to 90 per cent acrylamide links and an active principle selected from the group consisting of 3-ethyl-4(1-methyl-5-imidazolyl)-tetrahydrofuran-2-one, atropine, 3-methoxy-6-sulphanilamindopyridazine, .beta.-dimethylaminoethyl-p-butylaminobenzoate, neamine and 5-iodo-2-desoxyuridine. The ophthalmological medicinal film is an oblong plate, 6 - 9 mm long, 3 - 5 mm wide and 0.2 - 0.6 mm thick consisting of at least one polymer selected from a homopolymer of an amide of acrylic acid having a molecular weight from 30,000 to 1,000,000, and a copolymer of an amide of acrylic acid with unsaturated compounds, the molecular weight of the copolymer being from 20,000 to 500,000, and containing from 10 to 90 per cent acrylamide links and the active principle, viz., 3-ethyl-4-(1-methyl-5-imida-zolyl)-tetrahydrofuran-2-one or atropine, or 3-methoxy-6-sulphanil-amidopyridazine, or .beta.-dimethylamino-ethyl-p-butylaminobenzoate, or neamine, or ?-iodo-2-desoxyuridine. The ophthalmological medicinal film is used for treatment of glaucoma of various forms, thrombosis of the central vein of the retina, atrophy of the optic nerve, for dilating the pupil and paralysis of accommodation, in treatment of keratitis, iritis, iridocyclitis, ulcers of the cornea, trachoma, herpetic keratitis uveitis, and adenoviral infections, in extraction of foreign objects from the eye, and in various interventions in the organ of vision.</p>
申请公布号 CA1039188(A) 申请公布日期 1978.09.26
申请号 CA19720154458 申请日期 1972.10.23
申请人 VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY I ISPYTATELNY INSTITUT MEDITSIN 发明人 KHROMOV, GENNADY L.;DAVYDOV, ANATOLY B.;MAICHUK, JURY F.;TISHINA, INNA F.
分类号 A61K9/00;A61K31/785;A61K31/79;C08L33/26;G02B1/04;(IPC1-7):61K47/00 主分类号 A61K9/00
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