Binding molecules for bcma and cd3

摘要

Disclosed is a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein: (a) the first binding domain binds to epitope cluster 3 of BCMA (CQLRCSSNTPPLTCQRYC); and (b) the second binding domain binds to the T cell CD3 receptor complex; and wherein epitope cluster 3 of BCMA corresponds to amino acid residues 24 to 41 of the sequence as depicted in SEQ ID NO: 1002.