| 摘要 |
1,131,126. 2-Vinyl-1-4-dihydroquinazoline derivatives. PFIZER Ltd. 7 March, 1967 [10 March, 1966],No. 10503/66. Heading C2C. Novel compounds of formula and pharmaceutically acceptable acid addition salts thereof wherein R<SP>1</SP> and R<SP>2</SP> each are H, halogen, C 1-4 alkyl or C 1-4 alkoxy, R<SP>3</SP> is C 1-4 alkyl or benzyl, and R<SP>4</SP> is an aromatic carbocyclic or heterocyclic group optionally substituted by one or more halogen atoms, C 1-4 alkyl, C 1-4 alkoxy, phenyl, hydroxy or nitro groups are prepared by reaction of an aldehyde R<SP>4</SP>- CHO with a quinazoline derivative of formula Pharmaceutical compositions in conventional forms for oral or parenteral administration and having action on the cardiovascular system comprise an above novel compound and one or more diluents or carriers therefor. |
