发明名称 HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
摘要 Provided herein are Aminopurine Compounds having the following structure: wherein R1, R2 and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
申请公布号 ZA200809356(B) 申请公布日期 2010.02.24
申请号 ZA20080009356 申请日期 2008.10.31
申请人 SIGNAL PHARMACEUTICALS LLC 发明人 ALBERS RONALD;AYALA LETICIA;CLAREEN STEVEN S;DELGADO MEDEROS MARIA M;HILGRAF ROBERT;HEGDE SAYEE G;HUGHES KEVIN;KOIS ADAM;PLANTEVIN-KRENITSKY VERONIQUE;MCCARRICK MEG;NADOLNY LISA;PALANKI MOORTHY S S;SAHASRAMUDHE KIRAN;SAPIENZA JOHN;SATOH YOSHITAKA;SLOSS MARIANNE K;SUDBECK ELISE;WRIGHT JONATHAN
分类号 A61K;A61P 主分类号 A61K
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