<p>New antibiotic agents produced by the cultivation of Zalerion arboricola are described. The agents are a cyclic lipopeptides with very high activity against human pathogens and of very low mammalian toxicity.</p>
申请公布号
EP0405998(A1)
申请公布日期
1991.01.02
申请号
EP19900307125
申请日期
1990.06.29
申请人
MERCK & CO. INC.
发明人
GIACOBBE, ROBERT A.;HENSENS, OTTO D.;LIESCH, JERROLD;SCHWARTZ, ROBERT E.;SCHMATZ, DENNIS M.