发明名称 |
PROCESS FOR PREPARATION OF COMPOUND WITH POTENTIAL PHYSIOLOGICAL PROPERTIES OF 1,1-DIETHYLCARBOXY-2-TRIFLUOROMETHYL-2-(URIDYL-1'-)-ETHYLENE |
摘要 |
A process for preparation of compound with potential physiological properties of 1,1-diethylcarboxy-2-trifluoromethyl-2-(uridyl-1'-)-ethylene by reaction of nucleophilic substitution between uracil which acts as nucleophile and 1,1-diethycarboxy-2-chloro-2-trifluoromethylethylene, in molecule of which chlorine atom is activated by two diethylcarboxygroups in the system of anhydrous solvents (diethyl-dimethylformamide ether) in the presence of anhydrous triethylamine as dehalogenating agent.
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申请公布号 |
UA23821(U) |
申请公布日期 |
2007.06.11 |
申请号 |
UA20070000359U |
申请日期 |
2007.01.15 |
申请人 |
O.O. BOHOMOLETS NATIONAL MEDICAL UNIVERSITY |
发明人 |
VELCHYNSKA OLENA VASYLIVNA |
分类号 |
A61K33/16;C07C21/00;C07D239/553 |
主分类号 |
A61K33/16 |
代理机构 |
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