发明名称 PROCESS FOR PREPARATION OF COMPOUND WITH POTENTIAL PHYSIOLOGICAL PROPERTIES OF 1,1-DIETHYLCARBOXY-2-TRIFLUOROMETHYL-2-(URIDYL-1'-)-ETHYLENE
摘要 A process for preparation of compound with potential physiological properties of 1,1-diethylcarboxy-2-trifluoromethyl-2-(uridyl-1'-)-ethylene by reaction of nucleophilic substitution between uracil which acts as nucleophile and 1,1-diethycarboxy-2-chloro-2-trifluoromethylethylene, in molecule of which chlorine atom is activated by two diethylcarboxygroups in the system of anhydrous solvents (diethyl-dimethylformamide ether) in the presence of anhydrous triethylamine as dehalogenating agent.
申请公布号 UA23821(U) 申请公布日期 2007.06.11
申请号 UA20070000359U 申请日期 2007.01.15
申请人 O.O. BOHOMOLETS NATIONAL MEDICAL UNIVERSITY 发明人 VELCHYNSKA OLENA VASYLIVNA
分类号 A61K33/16;C07C21/00;C07D239/553 主分类号 A61K33/16
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