<p>An antibiotic agent produced by the cultivation of Zalerion arboricola which is a cyclic lipopeptide with very high activity against human pathogens and of very low mammalian toxicity and its production, isolation, and use are described.</p>
申请公布号
EP0405997(A1)
申请公布日期
1991.01.02
申请号
EP19900307124
申请日期
1990.06.29
申请人
MERCK & CO. INC.
发明人
SCHWARTZ, ROBERT E.;WHITE, RAYMOND F.;LIESCH, JERROLD M.;HENSENS, OTTO D.;JOSHUA, HENRY;SCHMATZ, DENNIS M.;TKACZ, JAN S.;KAPLAN, LOUIS;SOSA, MARGARET S.;FOUNTOULAKIS, JIMMY M.;GIACOBBE, ROBERT A.;MASUREKAR, PRAKASH S.