Benzothiophene compound

摘要

A method for preventing or treating a disease selected from the group consisting of visceral pain, inflammatory pain, osteoarthritis pain, neuropathic pain, and fibromyalgia in a subject in need thereof, comprising administering to said subject an effective amount of the compound of the following formula (I) or a salt thereof:;
wherein R1, R2, R3, R4, R5, X and n are as described herein.

主权项

1. A method for treating a disease selected from the group consisting of visceral pain, inflammatory pain, osteoarthritis pain, neuropathic pain, and fibromyalgia in a subject in need thereof, comprising administering to said subject an effective amount of the compound of formula (I) or a salt thereof: wherein X is —O—, —CH2—, —NH—, or —N(C1-6 alkyl)-, n is an integer of 1 to 3, R1 is —H, halogen, or lower alkyl, R2 and R3 are each the same as or different from each other, and are —H, halogen, C1-6 alkyl, or halo-C1-6 alkyl, R4 is —H or -Lk-NH—R0, Lk is C1-6 alkylene or a bond, R0 is C1-6 alkyl, C1-6 alkylene-OH, or cycloalkyl,
provided that in a case where R4 is —H, X is —N(C1-6 alkyl)-, and R5 is —H or C1-6 alkyl.