Disclosed are 3'-N-desmethyl-3'-N-susbstituted-6-O-methyl-11-deoxy-11, 12- cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutic al compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
申请公布号
CA2325521(A1)
申请公布日期
1999.10.07
申请号
CA19992325521
申请日期
1999.03.11
申请人
ABBOTT LABORATORIES
发明人
MORT, NICHOLAS A.;GREER, JONATHON;DALTON, CHRISTOPHER R.;FREY, LISA MARIE;HAVIV, FORTUNA;KAMINSKI, MICHELE A.;RANDOLPH, JOHN;BRUNCKO, MILAN;SAUER, DARYL R.;CRAWFORD, BRADLEY W.