| 发明名称 |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| 摘要 |
Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, and X are as defined herein for Formula (IA) and Formula (IB), or a tautomer, prodrug, solvate, or salt thereof, pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
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| 申请公布号 |
US7579469(B2) |
申请公布日期 |
2009.08.25 |
| 申请号 |
US20030739208 |
申请日期 |
2003.12.18 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
KUZMICH DANIEL;LEE THOMAS WAI-HO;PROUDFOOT JOHN ROBERT;REGAN JOHN ROBINSON;THOMSON DAVID S.;HAMMACH ABDELHAKIM;RALPH MARK STEPHEN;ZINDELL RENEE;BEKKALI YOUNES;KIRRANE, JR. THOMAS MARTIN |
| 分类号 |
C07D471/02;C07D207/14;C07D209/08;C07D209/34;C07D209/44;C07D209/48;C07D211/14;C07D211/18;C07D211/46;C07D211/58;C07D211/60;C07D211/62;C07D211/74;C07D213/64;C07D213/68;C07D213/69;C07D213/74;C07D213/85;C07D215/06;C07D215/22;C07D215/227;C07D215/233;C07D215/42;C07D217/04;C07D231/56;C07D237/28;C07D239/42;C07D239/88;C07D239/90;C07D241/04;C07D241/08;C07D241/38;C07D241/42;C07D241/44;C07D243/08;C07D243/14;C07D265/22;C07D265/36;C07D279/12;C07D279/16;C07D295/084;C07D295/112;C07D295/15;C07D295/185;C07D295/205;C07D307/24;C07D307/68;C07D317/58;C07D401/04;C07D401/06;C07D401/10;C07D401/14;C07D405/06;C07D405/10;C07D409/06;C07D409/10;C07D413/06;C07D413/10;C07D417/06;C07D471/04;C07D487/08 |
主分类号 |
C07D471/02 |
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