| 发明名称 |
Compositions and Methods for Diagnosing and Treating Cancer |
| 摘要 |
An isolated antibody that specifically binds to an extracellular domain of human DLL4 and affects growth of a tumor comprising cancer stem cells is described. Also described is a method of treating cancer comprising administering a therapeutically effective amount of an anti-DLL4 antibody. |
| 申请公布号 |
US2016367667(A1) |
申请公布日期 |
2016.12.22 |
| 申请号 |
US201615167510 |
申请日期 |
2016.05.27 |
| 申请人 |
OncoMed Pharmaceuticals, Inc. |
发明人 |
GURNEY Austin;AXELROD Fumiko;HOEY Tim;SATYAL Sanjeev |
| 分类号 |
A61K39/395;A61N5/10;A61K31/4745;C07K16/30;A61K31/513 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
Redwood City CA US |
