| 发明名称 |
METHODS AND COMPOSITIONS FOR TARGETING POLYUBIQUITIN |
| 摘要 |
Anti-K63-linked polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided. |
| 申请公布号 |
US2016355577(A1) |
申请公布日期 |
2016.12.08 |
| 申请号 |
US201615153644 |
申请日期 |
2016.05.12 |
| 申请人 |
GENENTECH, INC. |
发明人 |
Kelley Robert F.;Matsumoto Marissa |
| 分类号 |
C07K16/18;G01N33/68;C07K14/47 |
主分类号 |
C07K16/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated antibody or antigen-binding fragment thereof that specifically binds to K63-linked polyubiquitin, comprising at least one hypervariable (HVR) sequence selected from HVR-H2 and HVR-L2 of any of SEQ ID NOs: 59-110 and 112, and 7-58 and 111, respectively. |
| 地址 |
South San Francisco CA US |
