发明名称 4-aminoethoxyindazole derivatives
摘要 This invention relates to dopamine D2 agonists of the formula <IMAGE> I wherein: Y is hydrogen, halogen, or C1-C6 alkoxy; R1 is hydrogen or C1-C6 alkyl; X is methylene, oxygen or carbonyl; Ar is phenyl or thienyl, each optionally substituted with 1-2 groups independently selected from C1-C6 alkoxy, C1-C6 alkyl, halogen, trifluoromethyl and phenyl; n=1-4, or pharmaceutically acceptable salts thereof. Dopamine D2 agonists are useful in the treatment of schizophrenia, Tourette's syndrome, drug and alcohol addiction, and also useful in the treatment of Parkinson's disease.
申请公布号 US5872144(A) 申请公布日期 1999.02.16
申请号 US19980024600 申请日期 1998.02.17
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 MEWSHAW, RICHARD ERIC;VERWIJS, ANTHONIE JOHAN
分类号 C07D231/56;C07D409/12;(IPC1-7):A61K31/415 主分类号 C07D231/56
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