| 发明名称 |
GRP94 DERIVED POLYPEPTIDES FOR INHIBITING PCSK9 AND METHODS OF USE |
| 摘要 |
The present invention relates to PCSK9 inhibitors and methods of use thereof. Specifically, the invention relates to PCSK9 cell-based assay, PCSK9 inhibiting polypeptides and derivatives thereof. The invention includes pharmaceutical compositions comprising a PCSK9 inhibitor polypeptide together with a pharmaceutically acceptable carrier and method for treating cardiovascular disorders, inflammatory diseases or inflammatory response to infection. |
| 申请公布号 |
WO2016147162(A1) |
申请公布日期 |
2016.09.22 |
| 申请号 |
WO2016IB51559 |
申请日期 |
2016.03.19 |
| 申请人 |
INSTITUT DE CARDIOLOGIE DE MONTREAL |
发明人 |
POIRIER, Steve;MAYER, Gaétan |
| 分类号 |
C07K14/47;A61K38/17;A61P3/06;A61P9/10;C07K14/00;C12N1/21;C12N5/10;C12N9/64;C12N15/12;C12N15/63;C12N15/85;C12Q1/02;C12Q1/68;G01N33/48 |
主分类号 |
C07K14/47 |
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