| 发明名称 |
PROCESS FOR PREPARING ESTROGEN-ANTAGONISTIC 11 ß-FLUORO-17a-ALKYLESTRA-1,3,5(10)-TRIENE-3,17-DIOLS HAVING A 7a-(?-ALKYLAMINO-?-PERFLUOROALKYL)ALKYL SIDE CHAIN AND a-ALKYL(AMINO)-?-PERFLUORO(ALKYL)ALKANES AND PROCESSES FOR THEIR PREPARATION |
| 摘要 |
The present invention relates to a new process for preparing estrogen-antagonistic 11 ß-fluoro-17a-alkylestra-1,3,5(10)-triene-3,17-diols of the general formula (I) having a 7a-(?-alkylamino-?-perfluoroalkyl)alkyl side chain and to a-alkyl(amino)-?-perfluoro(alkyl)alkanes of the general formula (II), to processes for their preparation and to the intermediates required for this purpose.
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| 申请公布号 |
WO2009027108(A1) |
申请公布日期 |
2009.03.05 |
| 申请号 |
WO2008EP07210 |
申请日期 |
2008.08.28 |
| 申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT;SANDER, MICHAEL;GROSSBACH, DANJA;DINTER, CHRISTIAN;HASSFELD, JORMA;VOIGTLAENDER, DAVID |
发明人 |
SANDER, MICHAEL;GROSSBACH, DANJA;DINTER, CHRISTIAN;HASSFELD, JORMA;VOIGTLAENDER, DAVID |
| 分类号 |
C07C211/15;C07C21/18;C07C33/42;C07C211/24;C07C211/29;C07C309/73;C07F9/54;C07J41/00 |
主分类号 |
C07C211/15 |
| 代理机构 |
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