| 发明名称 |
PYRIDOPYRIMIDINE PROTEIN TYROSINE PHOSPHATASE INHIBITORS |
| 摘要 |
The present invention comprises pyridopyrimidinediamine compounds of the general formula I: The compounds of the present invention are potent inhibitors of PTP1B. Accordingly, the invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, including diabetes, obesity, and diabetes-related diseases.
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| 申请公布号 |
US2009062276(A1) |
申请公布日期 |
2009.03.05 |
| 申请号 |
US20080259737 |
申请日期 |
2008.10.28 |
| 申请人 |
BERTHEL STEVEN JOSEPH;CHEUNG ADRIAN WAI-HING;KIM KYUNGJIN;LI SHIMING;THAKKAR KSHITIJ CHHABILBHAI;YUN WEIYA |
发明人 |
BERTHEL STEVEN JOSEPH;CHEUNG ADRIAN WAI-HING;KIM KYUNGJIN;LI SHIMING;THAKKAR KSHITIJ CHHABILBHAI;YUN WEIYA |
| 分类号 |
A61K31/519;A61K31/5377;A61P3/10;C07D471/04 |
主分类号 |
A61K31/519 |
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