发明名称 FORMS OF RIFAXIMIN AND USES THEREOF
摘要 The present invention relates to Rifaximin amorphous forms, to their use in medicinal preparations and to therapeutic methods using them.
申请公布号 US2016317507(A1) 申请公布日期 2016.11.03
申请号 US201615141099 申请日期 2016.04.28
申请人 Salix Pharmaceuticals, Ltd 发明人 Gushurst Karen S.;Yang Donglai;Bevill Melanie Janelle;Schultheiss Nathan Carl;Viscomi Giuseppe Claudio
分类号 A61K31/437 主分类号 A61K31/437
代理机构 代理人
主权项 1. A method of treating irritable bowel syndrome, diarrhea, microbe associated diarrhea, Clostridium difficile associated diarrhea, travelers' diarrhea, small intestinal bacterial overgrowth, Crohn's disease, chronic pancreatitis, pancreatic insufficiency, enteritis, colitis, hepatic encephalopathy, or pouchitis, comprising administering to a subject in need thereof an effective amount of an amorphous form of rifaximin, wherein the amorphous form exhibits an X-ray powder diffraction pattern having characteristic peaks expressed in degrees 2θ (+/−0.20 degree θ) at 7.3, 11.3-17.8, and 15.8 degrees 2θ.
地址 Bridgewater NJ US