| 发明名称 |
METHODS AND COMPOSITIONS TO REDUCE LIVER DAMAGE ASSOCIATED WITH CONDITIONS OR THERAPIES THAT AFFECT THE IMMUNE SYSTEM |
| 摘要 |
One side-effect arising from the use of antibodies against TNF receptor family members as therapeutics can be liver damage which precludes the completion of clinical trial. A novel LT-dependent pathway is described that mediates liver cell injury in several disease models. |
| 申请公布号 |
US2016250327(A1) |
申请公布日期 |
2016.09.01 |
| 申请号 |
US201615082898 |
申请日期 |
2016.03.28 |
| 申请人 |
THE UNIVERSITY OF CHICAGO |
发明人 |
Fu Yang-Xin |
| 分类号 |
A61K39/395;A61K31/713 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method to reduce liver damage in a mammal, the method comprising administering to the mammal an agent that interferes with the LT or TNF pathways. |
| 地址 |
Chicago IL US |
