Spectroscopic analysis of nutrient materials for use in a cell culture process

摘要

In some embodiments, aspects of the disclosure relate to methods of evaluating cell culture materials, for example, nutrient materials, or other materials that can be used in cell culture media.

主权项

1. A method of evaluating a nutrient material, the method comprising:
performing a Raman spectroscopic analysis on a sample of the nutrient material to obtain a Raman spectrum; and identifying a value of a quality parameter based on the Raman spectrum, the quality parameter relating to the nutrient material or to a cell culture grown using the nutrient material, wherein the quality parameter is a Day 8 pH or a Peak 5 or a Lactate Production Integral.