RUTHENIUM COMPOUND, DIAMINE COMPOUND, AND PROCESS FOR PRODUCING beta -AMINO -ALCOHOL

摘要

A ruthenium (Ru) compound which is useful as a catalyst for asymmetric hydrogenation; a diamine ligand; and a process for highly stereoselectively producing an optically active alcohol in high yield. The process comprises using a ruthenium compound represented by the general formula (1): Ru(Px)>n1<[DIAMINE](X)(Y) {wherein Px represents a phosphine ligand; DIAMINE represents an optically active diamine represented by the general formula (2): R?1>R<2>C*(NHR<5>)-(A)-R<3>R<4>C*(NH2) [wherein R<1> to R<4> each independently represents hydrogen, optionally substituted alkyl, etc.; A represents optionally substituted C1-3 alkylene optionally containing an ether bond, optionally substituted C3-8 cycloalkylene, etc.; R<5> represents optionally substituted alkyl, optionally substituted aralkyl, or optionally substituted aryl; and C* represents asymmetric carbon]; X and Y each independently represents an anion; and n1 is an integer of 1 or 2} as a catalyst for asymmetric hydrogenation to produce a beta -amino alcohol from an alpha -aminocarbonyl compound.