发明名称 |
METHODS OF IDENTIFYING ESSENTIAL PROTEIN DOMAINS |
摘要 |
Provided herein, in some aspects, are methods of determining whether a candidate protein, more specifically a functional domain of a candidate protein, is essential for viability of cells of interest using clustered regularly interspaced short palindromic repeat (CPJSPR)-Cas9 technology which holds great promise for genetic screening and for the discovery of therapeutic targets. |
申请公布号 |
WO2016123071(A1) |
申请公布日期 |
2016.08.04 |
申请号 |
WO2016US14862 |
申请日期 |
2016.01.26 |
申请人 |
COLD SPRING HARBOR LABORATORY |
发明人 |
VAKOC, CHRISTOPHER, H.;SHI, JUNWEI;KINNEY, JUSTIN, B. |
分类号 |
C12N15/63;C12N5/078;C12N5/09;C12N9/22;C12N15/113 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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