发明名称 MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF
摘要 Methods and compositions are provided for extending the half-life of a therapeutic agent. One or more half-life extending moieties may be attached to a therapeutic agent, thereby extending the half life of the therapeutic agent. The modified therapeutic agents (mTAs) comprising one or more half-life extending moieties attached to a therapeutic agent may be used to treat a disease or condition in a subject in need thereof.
申请公布号 US2016287713(A1) 申请公布日期 2016.10.06
申请号 US201414917689 申请日期 2014.09.12
申请人 THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH ;THE SCRIPPS RESEARCH INSTITUTE 发明人 SHEN Weijun;SCHULTZ Peter G.;MUPPIDI Avinash;CRAMERI Andreas;AHMAD Insha;YANG Pengyu
分类号 A61K47/48;A61K38/26;A61K38/18;A61K38/17;A61K45/06;A61K38/22 主分类号 A61K47/48
代理机构 代理人
主权项
地址 La Jolla CA US