发明名称 |
MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF |
摘要 |
Methods and compositions are provided for extending the half-life of a therapeutic agent. One or more half-life extending moieties may be attached to a therapeutic agent, thereby extending the half life of the therapeutic agent. The modified therapeutic agents (mTAs) comprising one or more half-life extending moieties attached to a therapeutic agent may be used to treat a disease or condition in a subject in need thereof. |
申请公布号 |
US2016287713(A1) |
申请公布日期 |
2016.10.06 |
申请号 |
US201414917689 |
申请日期 |
2014.09.12 |
申请人 |
THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH ;THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
SHEN Weijun;SCHULTZ Peter G.;MUPPIDI Avinash;CRAMERI Andreas;AHMAD Insha;YANG Pengyu |
分类号 |
A61K47/48;A61K38/26;A61K38/18;A61K38/17;A61K45/06;A61K38/22 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
La Jolla CA US |