| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an improved composition for the treatment or prevention of hyperlipemia, atherosclerosis and other vascular conditions. <P>SOLUTION: The invention provides compositions, therapeutic combinations and methods including (a) at least one peroxisome proliferator-activated receptor activator, and (b) at least one substituted azetidinone or substituted β-lactam sterol absorption inhibitor which can be useful for treating vascular conditions, diabetes, obesity and lowering plasma levels of sterols. As an example of treatable vascular conditions, hyperlipemia (for example, atherosclerosis, hypercholesterolemia or sitosterolemia) is exemplified. <P>COPYRIGHT: (C)2008,JPO&INPIT |
