| 发明名称 |
CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES |
| 摘要 |
PROBLEM TO BE SOLVED: To provide carbohydrate-based vaccines.SOLUTION: The present invention relates to compounds of formula (I) defined by A[L-CH-CA], tautomers, and pharmaceutically acceptable salts thereof. (A is a carbohydrate antigen of 1-10,000 carbohydrate monomers; L is a linker molecule; CH is a disaccharide or trisaccharide; CA is a ceramide moiety represented by the formula in the figure; and p is the number of residues -L-CH-CA bound to the carbohydrate antigen A.)SELECTED DRAWING: Figure 2 |
| 申请公布号 |
JP2016183166(A) |
申请公布日期 |
2016.10.20 |
| 申请号 |
JP20160089305 |
申请日期 |
2016.04.27 |
| 申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E V;UNIVERSITAETSSPITAL BASEL |
发明人 |
PETER H SEEBERGER;PIERRE STALLFORTH;GENNARO DE LIBERO;MARCO CAVALLARI |
| 分类号 |
C07H15/04;A61K39/00;A61K39/002;A61K39/02;A61K39/12;A61K47/48;A61P31/00;A61P31/04;A61P31/06;A61P31/10;A61P31/12;A61P31/14;A61P31/16;A61P31/18;A61P31/20;A61P31/22;A61P33/00;A61P33/06;A61P35/00;A61P35/02 |
主分类号 |
C07H15/04 |
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