Drug eluting stent and a guide catheter device assembly for implanting the same

摘要

The present invention relates to a drug eluting stent for delivering therapeutic agents to a body lumen. The stent includes an expandable substrate configured for implantation in a vessel of a human body and a therapeutic agent composition coated over the stent. The balloon catheter shaft has a resilient unit that helps to transmit a force to the distal end, thereby helping to cross lesions.

主权项

1. A drug eluting stent for delivering therapeutic agents to a body lumen, the stent comprising:
a stent comprising a expandable substrate configured to be implanted in a vessel of a human body; and a therapeutic agent composition coated over the stent, the therapeutic agent composition comprising anticoagulants, Platelet Glycoprotein IIb/IIIa Receptor blocker or antagonist, and a cytostasis or cytotoxic agent, wherein, the proportion of the anticoagulants, the Platelet Glycoprotein IIb/IIIa Receptor blocker or antagonist, and the cytostasis or cytotoxic agent having a range of 1:0.15:0.5 to 1:0.2:1, and edges of the stent have a 3-30 times higher concentration of drugs as compared to middle segment of the stent to obtain a desired release profile of the coated composition.