发明名称 METHOD OF MANUFACTURING STEREOISOMERS OF BUPRENORPHINE AND ANALOGUES THEREOF
摘要 The present invention relates to a method of preparing a compound of Formula II-a' or Formula II-b', wherein R' represents hydrogen or a linear, branched and/or cyclic alkyl or alkenyl group having 1 to 10 carbon atoms; R II represents a linear, branched and/or cyclic alkyl or alkenyl group having 1 to 10 carbon atoms; R III represents hydrogen or a linear, branched and/or cyclic alkyl or alkenyl group having 1 to 10 carbon atoms or a linear, branched and/or cyclic alkoxy group having 1 to 10 carbon atoms; R IV represents hydrogen or a linear, branched and/or cyclic alkyl group having 1 to 10 carbon atoms or an optionally substituted aryl or alkylaryl group having 6 to 40 carbon atom or acetyl or silyl or a protective group; and R V represents hydrogen or a methyl group; wherein R I and R" are different from each other.
申请公布号 EP3067357(A1) 申请公布日期 2016.09.14
申请号 EP20150158586 申请日期 2015.03.11
申请人 SIEGFRIED AG 发明人 SAHLI, STEFAN;WEBER, BEAT THEODOR
分类号 C07D489/09 主分类号 C07D489/09
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