PREVENTIVE OR THERAPEUTIC AGENT FOR FREQUENT URINATION AND URINARY INCONTINENCE

摘要

A preventive or therapeutic agent for frequent urination and urinary incontinence containing as an active ingredient, a 1,4-benzodioxine derivative represented by the general formula (I): (wherein A represents an aryl group or a C3-8 cycloalkyl group, R1 and R2 are the same or different and represent a hydrogen atom, a halogen atom, a C1-6 alkyl group, a trifluoromethyl group, a C1-6 alkoxy group, an aryl group, an aryloxy group or an aryl C1-6 alkyloxy group (the aryl group, aryloxy group or aryl C1-6 alkyloxy group may be optionally substituted with one or two halogen atoms), or R1 and R2 are combined to represent -OCH2O-, R3 represents a hydrogen atom or a C1-6 alkyl group, R4 represents a hydrogen atom or CO2R5, R5 represents a hydrogen atom or a C1-6 alkyl group, X represents a divalent group having a moiety of the general formula (wherein n represents 1 or 2), or (III) ) or a pharmacologically acceptable salt thereof.