发明名称 |
Gremlin-1 antibody |
摘要 |
The present invention relates to a Gremlin-1 antibody that inhibits Gremlin-1 in a manner independent of bone morphogenetic protein (BMP) or vascular endothelial growth factor receptor-2 (VEGFR-2), thus providing the effect of treating cancer. The antibody of the present invention inhibits cell migration, cell invasion and cell proliferation which are dependent on Gremlin-1, and therefore, can be effectively used in treating cancer or immune disease. |
申请公布号 |
AU2013232855(B2) |
申请公布日期 |
2016.10.27 |
申请号 |
AU20130232855 |
申请日期 |
2013.03.15 |
申请人 |
SNU R&DB Foundation;Kim, Hyun |
发明人 |
Kim, Hyun Kee;Chung, Junho;Kim, Min Soo;Yoon, Soo Min |
分类号 |
C07K16/18;A61K39/395;A61P35/00;G01N33/53 |
主分类号 |
C07K16/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|