发明名称 Gremlin-1 antibody
摘要 The present invention relates to a Gremlin-1 antibody that inhibits Gremlin-1 in a manner independent of bone morphogenetic protein (BMP) or vascular endothelial growth factor receptor-2 (VEGFR-2), thus providing the effect of treating cancer. The antibody of the present invention inhibits cell migration, cell invasion and cell proliferation which are dependent on Gremlin-1, and therefore, can be effectively used in treating cancer or immune disease.
申请公布号 AU2013232855(B2) 申请公布日期 2016.10.27
申请号 AU20130232855 申请日期 2013.03.15
申请人 SNU R&DB Foundation;Kim, Hyun 发明人 Kim, Hyun Kee;Chung, Junho;Kim, Min Soo;Yoon, Soo Min
分类号 C07K16/18;A61K39/395;A61P35/00;G01N33/53 主分类号 C07K16/18
代理机构 代理人
主权项
地址