| 摘要 |
1. Process for preparing 5(6)-thiocyano-benzimidazole derivatives of general formula I see diagramm : EP0080554,P5,F2 wherein R represents hydrogen, halogen, C1-4 alkyl, C1-3 alkoxy or trifluoromethyl, R**1 represents amino or C1-4 alkoxycarbonylamino, and the salts thereof, characterised in that a compound of general formula II see diagramm : EP0080554,P5,F5 wherein R is as hereinbefore defined, is selectively reduced with iron to yield the compound of general formula III see diagramm : EP0080554,P5,F6 wherein R is as hereinbefore defined, which is reacted either with a cyanamide of general formula IV R**3 - NHCN wherein R**3 represents hydrogen or C1-4 alkoxycarbonyl, or with a halocyanogen of general formula V HlgCN wherein Hlg represents chlorine or bromine. |
| 申请人 |
CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. |
发明人 |
GONCZI, CSABA, DR., DIPL.ING.CHEM.;KORBONITS, DEZSO, DR., DIPL.ING.CHEM.;PALOSI, ENDRE, DIPL.ING.CHEM.;KISS, PAL, DR., DIPL.ING.CHEM.;HEJA, GERGELY, DR., DIPL.ING.CHEM.;KUN, JUDIT, DIPL.ING.CHEM.;SZOMOR GEB. WUNDELE, MARIA, DIPL.ING.CHEM.;SZVOBODA GEB. KANZEL, IDA, DIPL. ING. CHEM.;MARVANYOS, EDE, DIPL.ING.CHEM.;KOVACS GEB. MINDLER, VERA DIPL.ING.CHEM.;NAGY GEB. KORANYI, LIVIA, DIPL.ING.CHEM. |
