<p>Sterile pharmaceutical compositions for use in therapy especially inactivated vaccines for use in prophylaxis, are prepared by inactivating a live virus or bacterium with ascorbic acid and/or a salt thereof in the presence of oxygen and a source of heavy metal ions. Methods of treating animals, including humans, with such compositions are also disclosed.</p>
申请公布号
DE3886332(D1)
申请公布日期
1994.01.27
申请号
DE19883886332
申请日期
1988.09.26
申请人
BEECHAM INC., WHITE HALL, ILL., US
发明人
BORDT, DALE, WHITE HALL, IL 62092, US;DRAAYER, HANS, WHITE HALL, IL 62092, US