CYCLOSPORIN DERIVATIVES AND DERIVATIVE CONJUGATES

摘要

TITLE Cyclosporin Derivatives and Derivative Conjugates Cyclosporin compounds having a reactive residue attached to an intact cyclosporin ring, (and in particular compounds wherein the reactive residues are derivatives of a 2-N-methyl-(R)-((E)-2-butenyl)-4-methyl-L-threonine moiety on the intact cyclosporin ring), are used in the production of cyclosporin conjugates and conjugate complexes.