发明名称 SYNTHESIS OF ISOIMIDE OF CHLORINS AND BACTERIOCHLORINS AND THEIR USE FOR DIAGNOSIS AND TREATMENT OF CANCER
摘要 <p>Compounds having utility as light absorbing compounds, especially in the area of photodynamic therapy. Such compounds have formula (I), where z is = 0 or NR14; R14 is alkyl or substituted alkyl, R1 is an amino acid group, a polyamine group, a polyether group or OR13 where R13 is alkyl; R4 through R11 are -H, -OH, alkyl, alkylene, -OR16 where R16 is H, alkyl or aryl, or a carbonyl containing group, provided that: R4 may be taken together with R5 to form =O; R6 may be taken together with R7 to form =O; R8 may be taken together with R9 to form =O; R10 may be taken together with R11 to form =O; and R4 and R7 may together form a chemical bond and R8 and R11 may together form a chemical bond; and R12 is hydrogen or lower alkyl; provided that if one z is 0, the other z is -NR14.</p>
申请公布号 WO1997032885(A1) 申请公布日期 1997.09.12
申请号 US1997003891 申请日期 1997.03.07
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