| 摘要 |
<p>Compounds of formula (I): <CHEM> or a pharmaceutically acceptable salt thereof, wherein R1 is C1-5 alkyl optionally substituted by NHR6, (wherein R6 is hydrogen or C1-5 alkylcarbonyl) or by phenyl or naphthyl optionally substituted by halogen, C1-5 alkyl or C1-5 alkoxy or by dihydrobenzofuran-2-yl, optionally substituted in the benzo moiety by C1-5 alkyl, C1-5 alkoxy, hydrogen or trifluoromethyl; R2 and R5 are the same or different and each is hydroxy, C1-5 alkoxy, C2-6 alkylcarbonyl or amino optionally substituted by C1-5 alkyl; R3 is C1-5 alkyl optionally substituted by the group -NHR7, wherein R7 is hydrogen, C1-5 alkyl or C2-6 alkylcarbonyl; and R4 is phenyl optionally substituted by halogen, C1-5 alkoxy, trifluoromethyl or C1-5 alkyl having antihypertensive activity, a process for their preparation and their use.</p> |
