| 摘要 |
The present invention relates to the use of the peptides of the general formula: A-B-L-Phe (or L-Ala)-D-Lys-L-Phe-Z-OH, I where A represents one of the following groups: H-L-Met, H-L-Met(O), H-L-Met(O2), desamino-Met, desamino-Met(O) or desamino-Met(O2), B represents one of the following di-peptide fragments: Glu-His or Ala-Ala, where one amino acid residue of this di-peptide fragment can occur in the D form, and Z is either absent, or represents the amino acid residue Gly, or is the peptide fragment (10-16)-ACTH, where the amino acid L-Lys may be replaced, if desired, by D-Lys at position 11 of the (10-16)-ACTH fragment, and the functional derivatives thereof in promoting axonal regeneration.
|
