| 发明名称 |
USE OF IMIDAZOLE DERIVATIVES FOR PREPARING PHARMACEUTICAL COMPOSITION SHOWING ACTIVITY TO ANGIOTENSIN RECEPTORS AT<SB>1</SB> AND AT<SB>2</SB>, SOME OF THESE COMPOUNDS, METHOD OF SYNTHESIS OF IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
| 摘要 |
FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention proposes a new agent, pharmaceutical compositions based on said for treatment of patients with sicknesses associated with anomal stimulation of AT<SB>1</SB> and AT<SB>2</SB> receptors - the compound of the formula (I): <EMI ID=0.250 HE=24 WI=54 TI=CHI>. Radical values are given in the invention claim. Invention proposes also new compounds showing the above indicated activity and methods of their synthesis. EFFECT: improved method of synthesis, valuable pharmacological properties. 15 cl, 87 ex
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| 申请公布号 |
RU2141321(C1) |
申请公布日期 |
1999.11.20 |
| 申请号 |
RU19960120211 |
申请日期 |
1995.02.27 |
| 申请人 |
RUSSEL' JUKLAF |
发明人 |
ALAN KORB'E;P'ER DEPRE;MISHEL' FORTEHN;ZHAK GIJOM;BERTRAN EHKMAN |
| 分类号 |
C07D233/64;A61K31/415;A61K31/4166;A61P3/08;A61P3/10;A61P9/00;A61P9/08;A61P9/10;A61P9/12;A61P13/02;A61P13/12;A61P15/00;C07D233/54;C07D233/68;C07D233/70;C07D233/72;C07D233/84;C07D233/86;C07D233/90;C07D403/06;C07D409/12;(IPC1-7):A61K31/415 |
主分类号 |
C07D233/64 |
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