Methods for treating circadian rhythm disorders and sleep disorders are described. The method involves oral administration of a sustained release composition of melatonin to produce a normal melatonin pattern when the normal pattern has been disrupted or is missing.
申请公布号
WO9503043(A1)
申请公布日期
1995.02.02
申请号
WO1994US08365
申请日期
1994.07.25
申请人
STATE OF OREGON, ACTING BY AND THROUGH THE OREGON
发明人
LEWY, ALFRED, J.;SACK, ROBERT, L.;PARROTT, KEITH, A.;AYRES, JAMES, W.