| 发明名称 |
IL-1 receptor based cytokine traps |
| 摘要 |
Fusion polypeptides capable of binding interleukin-1 (IL-1) to form a nonfunctional complex are provided and nucleic acid molecules encoding the fusion polypeptides. The fusion ploypeptides form dimers to function as IL-1 antagonists.
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| 申请公布号 |
US6927044(B2) |
申请公布日期 |
2005.08.09 |
| 申请号 |
US20020282162 |
申请日期 |
2002.10.28 |
| 申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
STAHL NEIL;YANCOPOULOS GEORGE D. |
| 分类号 |
A61K38/00;A61K38/17;C07H21/04;C07K14/715;C07K16/24;C12N15/09;C12P21/04;(IPC1-7):C12P21/04 |
主分类号 |
A61K38/00 |
| 代理机构 |
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