| 发明名称 | Spiro-oxindole compounds and their use as therapeutic agents | ||
| 摘要 | This invention is directed to spiro-oxindole compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. | ||
| 申请公布号 | US9458178(B2) | 申请公布日期 | 2016.10.04 |
| 申请号 | US201414542367 | 申请日期 | 2014.11.14 |
| 申请人 | Xenon Pharmaceuticals Inc. | 发明人 | Chafeev Mikhail;Chowdhury Sultan;Fraser Lauren;Fu Jianmin;Langille Jonathan;Liu Shifeng;Sun Jianyu;Sun Shaoyi;Sviridov Serguei;Wood Mark;Zenova Alla Yurevna;Jia Qi;Cadieux Jean-Jacques Alexandre;Gauthier Simon J.;Douglas Amy Frances;Hsieh Tom;Chakka Nagasree;Cikojevic Zoran |
| 分类号 | C07D513/20;C07D491/10;C07D491/107;C07D491/20;C07D491/22;C07D495/20;C07D498/20;C07D519/00 | 主分类号 | C07D513/20 |
| 代理机构 | Seed IP Law Group PLLC | 代理人 | Seed IP Law Group PLLC |
| 主权项 | 1. A compound of formula (V): wherein: R9 is hydrogen, diphenylmethyl, [5-(trifluoromethyl)furan-2-yl]methyl, (2R)-tetrahydrofuran-2-ylmethyl, pyridin-2-ylmethyl, (2R)-1,4-dioxan-2-ylmethyl, or (2S)-1,4-dioxan-2-ylmethyl; as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof. | ||
| 地址 | Burnaby CA | ||