| 发明名称 | Multimer for immunostimulation | ||
| 摘要 | The invention relates to a multimeric non-coding nucleic acid molecule for modulating the activity of the human or animal immune system, and to a preparation process therefore and a vaccine which comprises the multimeric non-coding nucleic acid molecule. | ||
| 申请公布号 | US9499815(B1) | 申请公布日期 | 2016.11.22 |
| 申请号 | US200712300295 | 申请日期 | 2007.05.11 |
| 申请人 | Mologen AG | 发明人 | Schroff Matthias;Wittig Burghardt;Schmidt Manuel;Loehr Janine |
| 分类号 | C12N15/113;C12N15/117 | 主分类号 | C12N15/113 |
| 代理机构 | 24IP Law Group | 代理人 | 24IP Law Group ;DeWitt Timothy R |
| 主权项 | 1. A multimeric molecule for modulating the activity of the human or animal immune system, comprising: at least two covalently closed stem-loop monomer structures, at least one G structures, wherein the molecule comprises the base sequence N1N2CGN3N4 wherein N1N2 is an element from the group of GT, GG, GA, AT or AA, N3N4 is an element from the group of CT or TT, and C is deoxycytosine, G is deoxyguanosine, A is deoxyadenosine, and T is deoxythymidine. | ||
| 地址 | Berlin DE | ||