发明名称 |
NOVEL ESTERIFIED CELLULOSE ETHERS OF HIGH MOLECULAR WEIGHT AND HOMOGENEITY |
摘要 |
Esterified cellulose ethers which have i) as ester groups aliphatic monovalent acyl groups or a combination of aliphatic monovalent acyl groups and groups of the formula ——C(O)—R—COOA wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, ii) a weight average molecular weight Mw of from 80,000 Dalton to 220,000 Dalton, iii) a Polydispersity Mw/Mn of from 1.3 to 4.0, and iv) an Mz/Mn of not more than 18.5, when the weight average molecular weight Mw, the number average molecular weight Mn and the z-average molecular weight Mz are measured by SEC-MALLS using as mobile phase a mixture produced from 40 parts by volume of acetonitrile and 60 parts by volume of aqueous buffer containing 50 mM NaH2—PO4 and 0.1 M NaNO3. are useful as enteric polymers for pharmaceutical dosage forms. |
申请公布号 |
EP3107940(A1) |
申请公布日期 |
2016.12.28 |
申请号 |
EP20150703205 |
申请日期 |
2015.01.27 |
申请人 |
Dow Global Technologies LLC |
发明人 |
PETERMANN, Oliver;SPREHE, Matthias;BRACKHAGEN, Meinolf |
分类号 |
C08B13/00;A61K9/16;A61K47/38;C08B11/20 |
主分类号 |
C08B13/00 |
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