| 发明名称 |
PEPTIDES HAVING OSTEOBLAST GROWTH-PROMOTING ACTIVITY AND USE THEREOF |
| 摘要 |
The present invention provides a novel peptide having bone formation-promoting effect and chondrocyte growth-promoting effect, in particular, a peptide having osteoblast growth-promoting activity, having 100 amino acid residues or less comprising an amino acid sequence selected from;(a) Val-Asn-Pro-Glu-Ser-Glu-Glu-Glu-Asp-Glu-Ser-Ser-Pro-Tyr-Glu (SEQ ID NO: 1),
(b) an amino acid sequence derived from the amino acid sequence (a) by conservative substitution or deletion of 1 to 3 amino acids, and
(c) an amino acid sequence consisting of at least four contiguous amino acids of the amino acid sequence (a) or (b), or
a derivative thereof or a salt thereof. |
| 申请公布号 |
US2016362466(A1) |
申请公布日期 |
2016.12.15 |
| 申请号 |
US201515121471 |
申请日期 |
2015.02.25 |
| 申请人 |
PHARMA FOODS INTERNATIONAL CO., LTD. |
发明人 |
YAMAZAKI Chihiro;AN Ji-Yeong;HARADA Seiyu;WATABE Kazuya;KIM Mujo |
| 分类号 |
C07K14/51;A23L33/18;A61K8/64 |
主分类号 |
C07K14/51 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A peptide having osteoblast growth-promoting activity, having 100 amino acid residues or less comprising an amino acid sequence selected from
(a) Val-Asn-Pro-Glu-Ser-Glu-Glu-Glu-Asp-Glu-Ser-Ser-Pro-Tyr-Glu (SEQ ID NO: 1), (b) an amino acid sequence derived from the amino acid sequence (a) by conservative substitution or deletion of 1 to 3 amino acids, and (c) an amino acid sequence consisting of at least four contiguous amino acids of the amino acid sequence (a) or (b), or a derivative thereof or a salt thereof. |
| 地址 |
Kyoto JP |
