发明名称 |
METHOD OF TREATING A DOPAMINE RELATED DISORDER IN A SUBJECT BY ADMINISTERING LEVODOPA, IN COMBINATION WITH A DOPAMINE DECARBOXYLASE INHIBITOR AND A CATECHOL-O-METHYLTRANSFERASE INHIBITOR |
摘要 |
The invention relates to a method of treating a dopamine related disorder in a subject, the method comprises the steps of administering therapy to a subject, the therapy comprising a plurality of doses of levodopa over a selected time period, in combination with a dopamine decarboxylase inhibitor (DDI) and a catechol-O-methyltransferase (COMT) inhibitor, wherein: (i) the dose of levodopa is lower; (ii) the dose of DDI is lower; (iii) the dosing of levodopa is less frequent; and/or (iv) the dosing of DDI is less frequent As compared with a reference regimen over the selected time period. |
申请公布号 |
WO2017039525(A1) |
申请公布日期 |
2017.03.09 |
申请号 |
WO2016SE50828 |
申请日期 |
2016.09.05 |
申请人 |
LOBSOR PHARMACEUTICALS AKTIEBOLAG |
发明人 |
BOLSÖY, Roger |
分类号 |
G01N33/94;A61K31/198;A61K31/277;A61P25/00;A61P25/16;G01N33/15;G01N33/487 |
主分类号 |
G01N33/94 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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